Enfermedad celiaca silente en pacientes adultos con enfermedades tiroideas autoinmunes
Resumen
Introducción: la enfermedad celiaca puede estar asociada en forma silente a las tiroiditis autoinmunes.
Objetivo: determinar la presencia de enfermedad celiaca silente en pacientes con tiroiditis autoinmunes.
Metodología: estudio observacional, prospectivo, multicéntrico realizado en pacientes adultos con tiroiditis de Hashimoto y enfermedad de Graves de tres centros hospitalarios de Paraguay en años 2018-2019. Se determinó la presencia anticuerpos IgA antitransglutaminasa e IgA sérica en aquellos que aceptaron participar del estudio. Se midieron además variables demográficas y clínicas. El estudio fue aprobado por el Comité de Ética de la Universidad Nacional de Itapúa.
Resultados: se contactaron 87 pacientes, pero la muestra final estuvo constituida por 22 sujetos. La edad media fue 50 años, con predominio del sexo femenino (77%). Se detectaron anticuerpos para enfermedad celiaca en 3 casos (13%) y todos fueron confirmados con biopsia duodenal.
Conclusiones: la frecuencia de enfermedad celiaca silente en pacientes con tiroiditis de Hashimoto y enfermedad de Graves fue 13%.
Palabras clave
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Facultad de Ciencias Médicas. Universidad Nacional de Asunción
